
In Denver, the Rockies hold a 56-51 edge all-time, last sweeping the Cardinals at Coors Field during the 2010 season.
Speaking of that year, that Cardinals-Rockies series contained one of the top 10 games for the Rockies in the past decade, according to this list from MLB.com’s Thomas Harding. On July 6, St. Louis took a six-run lead into the bottom of the ninth before the Rockies rallied for an improbable win.
Colorado scored nine times in the bottom of the ninth, with Chris Iannetta hitting a three-run homer, Carlos Gonzalez hitting an RBI single as part of a 4-for-6 night, and Seth Smith capping the rally with a game-winning three-run shot off Cardinal reliever Ryan Franklin to send the Coors Field crowd into a frenzy.
The Rockies would also win the next night, 8-7, on a walkoff when Iannetta, the first batter of the bottom of the ninth, would hit a solo homer off Cardinal reliever Evan MacLane. It would be the third straight walkoff win for Colorado that season, with their July 4 game against the San Francisco Giants also ending in the game’s final frame.
St. Louis has also had its last-minute moments in Denver as well. On April 8, 2003, after Todd Helton‘s seventh-inning home run knotted the game at 12, the Cardinals prevailed in 13 innings when Mike Matheny‘s three-run shot handed the visitors a 15-12 edge. Cal Eldred pitched a perfect bottom of the inning to preserve the win.